Carole Linster is an Associate Professor at the University of Luxembourg where she is heading the Enzymology & Metabolism Group at the Luxembourg Centre for Systems Biomedicine. After a PhD in biomedical sciences at the de Duve Institute, UCLouvain (Brussels), she moved to UCLA (Los Angeles) for a postdoc, followed by a second postdoc back at the de Duve Institute. Her main research interests include metabolomics-assisted enzyme function discovery, with a focus on metabolite damage and repair reactions, and elucidating molecular mechanisms underlying inborn errors of metabolism. Carole Linster and co-workers discovered several new metabolite repair enzymes involved in the breakdown of metabolic side products that are constantly formed in our cells through enzymatic side activities or unwanted chemical reactions. Her group recently co-led the identification of a novel rare neurodegenerative childhood disorder that is caused by the deficiency of one of those metabolite repair enzymes (NAXD), which is needed to convert damaged, inactive forms of NADH and NADPH back to the active cofactors. The Linster group also deploys increasing efforts towards disease modeling, in yeast and human cells as well as zebrafish, and drug repurposing for rare diseases.